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	<title>Comments on: V is for Varicella</title>
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		<title>By: Matthew Cottingham</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2486</link>
		<dc:creator>Matthew Cottingham</dc:creator>
		<pubDate>Thu, 15 Mar 2007 19:13:26 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2486</guid>
		<description>This is just a thought or two but it has been found in post-mortem studies that polio victims have viral fragments of the polio virus in their spinal cords. There are references that can be found on-line or through other research for this. The second thought is that if the chicken pox can recur later in life in the form of shingles, why is it unreasonable to assume that the same may be possible with the polio virus in people with post-polio syndrome?

    I have read the standard literature on post-polio syndrome, PPS and seen an almost universal claim that late effects are not caused by a recurrence of the virus. I would suggest an easy way to resolve the question. It would be simple to take blood samples from people with post-polio syndrome and look at the number of antibodies to the virus that are present against a control population of the same age who had never been reported as having had polio. This is a relatively cheap means of performing such research.

It does seem logical that if the chicken pox virus can lie dormant for many years and resurface as shingles, much the same could be true of other viral diseases, including poliomyelitis.

When I suffered severe problems from PPS, my physician failed to take the blood samples I requested and send them for analysis. I had located a laboratory with the capability to do this and gave my physician the address.  I had offered to pay cash to have it done as I was having the second acute attack of whatever it was that robbed me of an arm and leg, regardless of what insurance paid. 

The problem I had with all of this is that my initial polio occurred in late 1950-early 1951. I had had major involvement in breathing and limb function and later had an acute attack in 1981. The last attack was in 2002 when the doctor failed to pursue what might have been an instructive lead on PPS. The cost would have been paid out of pocket had the insurance refused payment. I changed physicians as a result of what I view as a lack of care. 

Each attack has left me a much weaker than the time immediately predeing the attack. I would argue at present that a recurrence of the polio virus may be a causative agent in at least some cases of post polio syndrome in much the same manner as there is a connection between chicken pox virus and shingles.

By the way, I also had chicken pox as a child but have not experienced shingles. I suspect late viral effects may be a bit of a matter of chance. 

I would also like to raise the question of: &quot;Does a person who has had a viral disease ever really kill all the virus in the body or does it lie more or less under control by the immune system?&quot; Is some sort of stasis achieved in the body? I believe these are legitimate questions that physicians should attempt to answer when the patient requests a test and is willing to cover all costs.

I personally believe my physician was negligent in this matter. No malpractice suit is in the works but the man was wrong in my opinion for not asking a question that would have been paid for by the patient. I still want an answer on behalf of all people with PPS. 

I am old enough to recall how physicians treated stomach ulcers when they attributed them to diet or stress and totally missed the microbiological connection. I was formerly a scientist and have certain credentials in microbiology as well as other disciplines. I am puzzled by the resistance of the medical community to any idea that is a bit new. Perhaps some wiser person can explain this to me. 

Sincerely,

Matthew
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		<content:encoded><![CDATA[<p>This is just a thought or two but it has been found in post-mortem studies that polio victims have viral fragments of the polio virus in their spinal cords. There are references that can be found on-line or through other research for this. The second thought is that if the chicken pox can recur later in life in the form of shingles, why is it unreasonable to assume that the same may be possible with the polio virus in people with post-polio syndrome?</p>
<p>    I have read the standard literature on post-polio syndrome, PPS and seen an almost universal claim that late effects are not caused by a recurrence of the virus. I would suggest an easy way to resolve the question. It would be simple to take blood samples from people with post-polio syndrome and look at the number of antibodies to the virus that are present against a control population of the same age who had never been reported as having had polio. This is a relatively cheap means of performing such research.</p>
<p>It does seem logical that if the chicken pox virus can lie dormant for many years and resurface as shingles, much the same could be true of other viral diseases, including poliomyelitis.</p>
<p>When I suffered severe problems from PPS, my physician failed to take the blood samples I requested and send them for analysis. I had located a laboratory with the capability to do this and gave my physician the address.  I had offered to pay cash to have it done as I was having the second acute attack of whatever it was that robbed me of an arm and leg, regardless of what insurance paid. </p>
<p>The problem I had with all of this is that my initial polio occurred in late 1950-early 1951. I had had major involvement in breathing and limb function and later had an acute attack in 1981. The last attack was in 2002 when the doctor failed to pursue what might have been an instructive lead on PPS. The cost would have been paid out of pocket had the insurance refused payment. I changed physicians as a result of what I view as a lack of care. </p>
<p>Each attack has left me a much weaker than the time immediately predeing the attack. I would argue at present that a recurrence of the polio virus may be a causative agent in at least some cases of post polio syndrome in much the same manner as there is a connection between chicken pox virus and shingles.</p>
<p>By the way, I also had chicken pox as a child but have not experienced shingles. I suspect late viral effects may be a bit of a matter of chance. </p>
<p>I would also like to raise the question of: &#8220;Does a person who has had a viral disease ever really kill all the virus in the body or does it lie more or less under control by the immune system?&#8221; Is some sort of stasis achieved in the body? I believe these are legitimate questions that physicians should attempt to answer when the patient requests a test and is willing to cover all costs.</p>
<p>I personally believe my physician was negligent in this matter. No malpractice suit is in the works but the man was wrong in my opinion for not asking a question that would have been paid for by the patient. I still want an answer on behalf of all people with PPS. </p>
<p>I am old enough to recall how physicians treated stomach ulcers when they attributed them to diet or stress and totally missed the microbiological connection. I was formerly a scientist and have certain credentials in microbiology as well as other disciplines. I am puzzled by the resistance of the medical community to any idea that is a bit new. Perhaps some wiser person can explain this to me. </p>
<p>Sincerely,</p>
<p>Matthew</p>
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		<title>By: Airdrie</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2485</link>
		<dc:creator>Airdrie</dc:creator>
		<pubDate>Tue, 24 Oct 2006 23:35:07 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2485</guid>
		<description>I chose to vaccinate my kids on the advice of my GP.  As a highschool teacher I have also seen some horror stories of teenage-chicken pox (high fever, missed school, bad scarring on the face).  I would strongly recommend readers have their kids vaccinated.  I also had shigles two years ago (had the pox in grade 3), and the shingles was HORRIBLE. I had a ring of blisters around my chest, and the pain and fever were unbearable. It stole three weeks of my life, in the prime of my life.  It was helped by retro-viral drugs, but may come back I&#039;m told. Just my two bits.
Are you coming to Northern Voice??</description>
		<content:encoded><![CDATA[<p>I chose to vaccinate my kids on the advice of my GP.  As a highschool teacher I have also seen some horror stories of teenage-chicken pox (high fever, missed school, bad scarring on the face).  I would strongly recommend readers have their kids vaccinated.  I also had shigles two years ago (had the pox in grade 3), and the shingles was HORRIBLE. I had a ring of blisters around my chest, and the pain and fever were unbearable. It stole three weeks of my life, in the prime of my life.  It was helped by retro-viral drugs, but may come back I&#8217;m told. Just my two bits.<br />
Are you coming to Northern Voice??</p>
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		<title>By: Rachel Cook, Minti</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2484</link>
		<dc:creator>Rachel Cook, Minti</dc:creator>
		<pubDate>Mon, 05 Jun 2006 03:41:14 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2484</guid>
		<description>Hi Julie, wow I had no idea. I haven&#039;t yet taken my son Codi to get his chicken pox vaccination which is free here in Australia for toddlers over 18 months of age. Wow, I admire your strength to go against the trend. This is an amazing experience, one that is really making me think carefully, I dread both decisions. You may like to post this at Minti to spread you experience to let parents make better informed decisions..ie. natural immunity vs scientific immunity...and link back to your blog. Minti is a friendly place with advice/experiences such as spanking, breast or bottle discussed in an healthy way.

Hope to see you there...

Cheers, Rachel</description>
		<content:encoded><![CDATA[<p>Hi Julie, wow I had no idea. I haven&#8217;t yet taken my son Codi to get his chicken pox vaccination which is free here in Australia for toddlers over 18 months of age. Wow, I admire your strength to go against the trend. This is an amazing experience, one that is really making me think carefully, I dread both decisions. You may like to post this at Minti to spread you experience to let parents make better informed decisions..ie. natural immunity vs scientific immunity&#8230;and link back to your blog. Minti is a friendly place with advice/experiences such as spanking, breast or bottle discussed in an healthy way.</p>
<p>Hope to see you there&#8230;</p>
<p>Cheers, Rachel</p>
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		<title>By: Derek K. Miller</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2483</link>
		<dc:creator>Derek K. Miller</dc:creator>
		<pubDate>Thu, 20 Apr 2006 23:16:27 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2483</guid>
		<description>Whoops, I should have written &quot;I don&#039;t want to *rant* about it&quot; not &quot;I don&#039;t want to want about it.&quot; Though I fear I did rant.</description>
		<content:encoded><![CDATA[<p>Whoops, I should have written &#8220;I don&#8217;t want to *rant* about it&#8221; not &#8220;I don&#8217;t want to want about it.&#8221; Though I fear I did rant.</p>
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		<title>By: Derek K. Miller</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2482</link>
		<dc:creator>Derek K. Miller</dc:creator>
		<pubDate>Thu, 20 Apr 2006 23:14:23 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2482</guid>
		<description>We had our duaghters vaccinated. I don&#039;t want to want about it, and I certainly don&#039;t want to be critical that you didn&#039;t, Julie. The chicken pox vaccine is relatively new, and plenty of people decide not to get it.

The key reason we did for our kids is that the vaccine, because it is not a live virus, provides immunity without the risk of shingles later in life. (The vaccine makers seem a bit reluctant to claim that, probably for liability reasons, but my wife and I both have biology degrees, and I can&#039;t see any reason that wouldn&#039;t be the case.)

Shingles can be debilitating if you get it at an advanced age or if it affects your face or eyes. Like you, Julie, we&#039;re not among those who are suspicious of vaccines -- we may be a bit overzealous, in fact, vaccinating our kids for nearly anything reasonably available. So it seemed an obvious choice to us, even if it isn&#039;t to everyone.

Since the vaccine didn&#039;t exist when I was a kid, I ended up getting chicken pox when I was 14, and the older you are, the worse it seems to be: I had a fever of 105 degrees and was in bed, completely non-functional, for nearly a week. My wife got it young and mildly, but then got shingles a couple of years ago in her mid-30s, and it was both excruciatingly painful for her and very tiring. And a single instance of the shingles recurrence of the virus is no guarantee it won&#039;t come back.

It&#039;s good that your kids got it young, since their symptoms are probably relatively mild in the long run. But for us, avoiding shingles in their future was a good argument for vaccination.

I think for vaccines in general, it is worth keeping in mind that those who denigrate vaccinations because of the perceived risks seem to forget the severity of the diseases they avoid. I haven&#039;t seen any actual statistical evidence of increased risks from MMR or polio vaccines. But even if those risks were there, the risks from actually contracting measles, mumps, rubella, or especially polio are massive. Just ask anyone old enough to have contracted polio, or to have post-polio syndrome (a recurrence, like shingles is).

Over human history, millions upon millions of people have been killed by viral infections that are now entirely preventable by vaccination, and bacterial ones treatable with antibiotics. Until recent decades, families routinely watched people (especially kids) die from them, or women who did not survive childbirth because of them. We should not forget that.</description>
		<content:encoded><![CDATA[<p>We had our duaghters vaccinated. I don&#8217;t want to want about it, and I certainly don&#8217;t want to be critical that you didn&#8217;t, Julie. The chicken pox vaccine is relatively new, and plenty of people decide not to get it.</p>
<p>The key reason we did for our kids is that the vaccine, because it is not a live virus, provides immunity without the risk of shingles later in life. (The vaccine makers seem a bit reluctant to claim that, probably for liability reasons, but my wife and I both have biology degrees, and I can&#8217;t see any reason that wouldn&#8217;t be the case.)</p>
<p>Shingles can be debilitating if you get it at an advanced age or if it affects your face or eyes. Like you, Julie, we&#8217;re not among those who are suspicious of vaccines &#8212; we may be a bit overzealous, in fact, vaccinating our kids for nearly anything reasonably available. So it seemed an obvious choice to us, even if it isn&#8217;t to everyone.</p>
<p>Since the vaccine didn&#8217;t exist when I was a kid, I ended up getting chicken pox when I was 14, and the older you are, the worse it seems to be: I had a fever of 105 degrees and was in bed, completely non-functional, for nearly a week. My wife got it young and mildly, but then got shingles a couple of years ago in her mid-30s, and it was both excruciatingly painful for her and very tiring. And a single instance of the shingles recurrence of the virus is no guarantee it won&#8217;t come back.</p>
<p>It&#8217;s good that your kids got it young, since their symptoms are probably relatively mild in the long run. But for us, avoiding shingles in their future was a good argument for vaccination.</p>
<p>I think for vaccines in general, it is worth keeping in mind that those who denigrate vaccinations because of the perceived risks seem to forget the severity of the diseases they avoid. I haven&#8217;t seen any actual statistical evidence of increased risks from MMR or polio vaccines. But even if those risks were there, the risks from actually contracting measles, mumps, rubella, or especially polio are massive. Just ask anyone old enough to have contracted polio, or to have post-polio syndrome (a recurrence, like shingles is).</p>
<p>Over human history, millions upon millions of people have been killed by viral infections that are now entirely preventable by vaccination, and bacterial ones treatable with antibiotics. Until recent decades, families routinely watched people (especially kids) die from them, or women who did not survive childbirth because of them. We should not forget that.</p>
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		<title>By: Katherine</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2481</link>
		<dc:creator>Katherine</dc:creator>
		<pubDate>Thu, 20 Apr 2006 20:53:46 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2481</guid>
		<description>So lovely to hear from you again here. Thanks for all these insights. I am glad the girls are on the mend.</description>
		<content:encoded><![CDATA[<p>So lovely to hear from you again here. Thanks for all these insights. I am glad the girls are on the mend.</p>
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		<title>By: Ed</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2480</link>
		<dc:creator>Ed</dc:creator>
		<pubDate>Thu, 20 Apr 2006 19:16:08 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2480</guid>
		<description>Hey Julie,

I believe that you are at risk of shingles as an adult because you had chicken pox some time in your life.  Here is a site that talks about it:

http://www.aftershingles.com/shingles.html

Mary and I went back and forth on whether to vaccinate Jared or not.  Could the vaccine fail and cause him to get them as an adult?  In the end, he got the vaccine.  The neighbor kids got the poxs last summer.  Oddly enough, one of the older kids got shingles causing chicken pox in the younger kids.  Jared had three spots on his back.  We are not totally sure if it was a very mild case of Chicken Pox or not.</description>
		<content:encoded><![CDATA[<p>Hey Julie,</p>
<p>I believe that you are at risk of shingles as an adult because you had chicken pox some time in your life.  Here is a site that talks about it:</p>
<p><a href="http://www.aftershingles.com/shingles.html" rel="nofollow">http://www.aftershingles.com/shingles.html</a></p>
<p>Mary and I went back and forth on whether to vaccinate Jared or not.  Could the vaccine fail and cause him to get them as an adult?  In the end, he got the vaccine.  The neighbor kids got the poxs last summer.  Oddly enough, one of the older kids got shingles causing chicken pox in the younger kids.  Jared had three spots on his back.  We are not totally sure if it was a very mild case of Chicken Pox or not.</p>
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		<title>By: Lucy</title>
		<link>http://www.julieleung.com/archives/2116/comment-page-1#comment-2479</link>
		<dc:creator>Lucy</dc:creator>
		<pubDate>Wed, 19 Apr 2006 18:54:58 +0000</pubDate>
		<guid isPermaLink="false">http://www.julieleung.com/wordpress/?p=2116#comment-2479</guid>
		<description>I didn&#039;t get mine vaccinated for that either yet.  I&#039;m fascinated by the people that assume that means I&#039;m &quot;anti-medicine&quot; and &quot;anti-science&quot;. 

Glad y&#039;al are feeling better. It can be SO rough trying to keep little ones entertained when all they want to do is itch-itch-itch!</description>
		<content:encoded><![CDATA[<p>I didn&#8217;t get mine vaccinated for that either yet.  I&#8217;m fascinated by the people that assume that means I&#8217;m &#8220;anti-medicine&#8221; and &#8220;anti-science&#8221;. </p>
<p>Glad y&#8217;al are feeling better. It can be SO rough trying to keep little ones entertained when all they want to do is itch-itch-itch!</p>
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